Tylosin is a macrolide-class antibiotic with a broad spectrum of activity against gram positive organisms and a limited range of gram negative organisms. It is found naturally as a fermentation product of Streptomyces fradiae.
Tylosin is used in veterinary medicine to treat bacterial infections in a wide range of species and has a high margin of safety.It has also been used as a growth promotant in some species, and as a treatment for colitis in companion animals.
Tylosin has been used to treat a variety of different diseases throughout the world. Differing formulations and licensing conditions will mean that it may not be a recognised method of treatment for certain conditions in certain countries. In general Tylosin is licensed for the treatment of infections caused by organisms susceptible to the drug, but it has also been used as a treatment of colitis in small animals, as a growth promotant in food producing animals, and as a way of reducing epiphora (tear staining) around the eyes of white faced dogs.
Examples of bacterial infections that could potentially be treated with Tylosin include respiratory infections, metritis, and acute mastitis in cattle; mastitis in sheep and goats; enteritis, pneumonia, erysipelas, and infectious arthritis in swine; and soft tissue infections in small animals.
Final titre: 12-14g/L
Fermentation time: 180hrs
Recovery yield: 75-80%
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