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| Position: Technologies --> Know-How--> Tech Opportunity |
| Manufacturing Teicoplanin by fermentation process |
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Teicoplanin is an antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis. It is a glycopeptide antibiotic extracted from Actinoplanes teichomyceticus, with a similar spectrum of activity to vancomycin. Its mechanism of action is to inhibit bacterial cell wall synthesis. Teicoplanin is marketed by Sanofi-Aventis under the trade name Targocid.
Technology data:
Status: commercial
Final titre: 5±0.5 g/l
Fermentation time: 168±12 hrs
Recovery yield: 55% |
| 发表时间：2008-11-13 |
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中文
