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Fermentation technology for Teicoplanin

Teicoplanin is an antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis. It is a glycopeptide antibiotic extracted from Actinoplanes teichomyceticus, with a similar spectrum of activity to vancomycin. Its mechanism of action is to inhibit bacterial cell wall synthesis. Teicoplanin is marketed by Sanofi-Aventis under the trade name Targocid.

Market:

Be in hare demand:1, 000kg/year(global 2005)

Price：12, 000-17, 000﹩（2006）

Technology data：

Final titre: 4±0.5 g/l

Fermentation time: 168±12 hrs

Recovery yield: 55%

发表时间：2008-10-24