Name: 4-Acetoxyazetidin-2-one (4-AA)
Other name: Acetoxysilyloxyazetidinone, 4-AA, AOSA
Use: Its mother nucleus of carbapenem antibiotic. Be used to synthesize meropenem, imipenem, etc.
CAS: 76855-69-1
Molecular formula: C13H25NO4Si Molecular weight: 287.43
Product Specification:
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White to buff crystal powder |
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Should be concordant with Reference standard |
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Should be concordant with Reference standard |
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Water content (Karl Fisher) |
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Yield of stage
Stage |
Yields (mol %) |
Yields w/w |
Amino preparation |
B1 |
81.41~91.22% |
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Epoxy butyric acid preparation |
A1 |
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Condensation preparation |
A2 |
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1.42-1.67on L-threonine |
Cyclic preparation |
A3 |
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0.526 |
Sili-ester preparation |
A4 |
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Hydrolysate preparation |
A5 |
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1.094-1.198 on A3 |
Oxide preparation |
A6 |
75.1~80.0%( on A5) |
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Ozone reaction |
A7 |
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A7 |
68.1~77.2%( on A6) |
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Successful Case: 10t/a industrial set is run well. The process is stable and commercial with international lead.
n High product quality, conform to Japanese product.
n , All reactions are done under normal temperature, no super low temperature.
n Lower production cost. Easy to get all materials.
n Small investment, good returns.
中文
