Manufacturing Coenzyme Q10 by Fermentation
Coenzyme Q10 (also known as ubiquinone, ubidecarenone, coenzyme Q, and abbreviated at times to CoQ10, CoQ, Q10, or Q) is a benzoquinone, where Q refers to the quinone chemical group, and 10 refers to the isoprenyl chemical subunits.
This oil-soluble vitamin-like substance is present in most eukaryotic cells, primarily in the mitochondria. It is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. Ninety-five percent of the human body’s energy is generated this way. Therefore, those organs with the highest energy requirements—such as the heart and the liver—have the highest CoQ10 concentrations.
Because of its ability to transfer electrons and therefore act as an antioxidant, Coenzyme Q is also used as a dietary supplement. When one is younger the body can synthesize Q10 from the lower-numbered ubiquinones such as Q6 or Q8.The elderly and sick may not be able to make enough, thus it is possible that Q10 becomes a vitamin later in life and in illness.]
According to the Mayo Clinic "CoQ10 has been used, recommended, or studied for numerous conditions, but remains controversial as a treatment in many areas." Further clinical results are needed to determine whether the supplementation with Coenzyme Q10 is beneficial for healthy people.
Our technology:
Producing strain: Pseudomonas denitrificans
Final titre: 2.5-3.0g/L
Recovery Yield: 60～75％
Status: commercial in 60M3 fermenter
Product Quality: comply with USP28、JP14 and CP2005
Process Flowchart:
Strain----seed----fermentation----microfiltration---drying----crash---extract----resin---decant---concentration---crystallization----finished CoQ10
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