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| 【主 题】 ： |
Ursodiol |
| 【联系人名】 ： |
Linna Green |
| 【电子邮件】 ： |
account@bocsci.com |
| 【联系电话】 ： |
1-631-559-9269 |
| 【发布日期】 ： |
2016-8-26 |
| 【详细说明】 ： |
Ursodeoxycholic acid (UDCS) is a cell protectant
used extensively to mitigate hepatic and biliary
diseases. Ursodeoxycholic acid may be used to study
its specific activities that range from reduction of
cholesterol absorpition, cholesterol gallstone
dissolution to suppression of immune response.IC50:
M1-family aminopeptidase: IC50 = 2.6 μM (Plasmodium
falciparum 3D7); NTCP: IC50 = 3.6 μM (human); HCT-
116: IC50 = >50 μM (human); GBM: IC50 = >50 μM
(human) Asbt: Ki= 75 μM (human)
Gallstone-dissolving drugs; Anti-neoplastic; For the
prevention and treatment of cholesterol gallstones;
Reduces hydrophobic bile acids and decreases both
lymphocyte reactivity and serum alkaline phosphatase
levels,IC50: M1-family aminopeptidase: IC50 = 2.6 μM
(Plasmodium falciparum 3D7); NTCP: IC50 = 3.6 μM
(human); HCT-116: IC50 = >50 μM (human); GBM: IC50 =
>50 μM (human) Asbt: Ki= 75 μM (human)
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English
