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| 【主 题】 ： |
Native Bacillus sp. Purine Nucleoside Phosphorylase |
| 【联系人名】 ： |
Lisa Clara |
| 【电子邮件】 ： |
contact@creative-enzymes.com |
| 【联系电话】 ： |
5166698109 |
| 【发布日期】 ： |
2016-5-18 |
| 【详细说明】 ： |
Purine nucleoside phosphorylase (also known as
PNPase) is an enzyme (EC 2.4.2.1) involved in
purine metabolism. PNP metabolizes adenosine into
adenine, inosine into hypoxanthine, and guanosine
into guanine, in each case creating ribose
phosphate. NP encodes the enzyme purine nucleoside
phosphorylase that together with adenosine
deaminase (ADA) serves a key role in purine
catabolism, referred to as the salvage pathway.
Mutations in either enzyme result in a severe
combined immunodeficiency (SCID). Confusingly, the
same abbreviation (PNPase), is also used for
another, otherwise unrelated, enzyme, namely
Polynucleotide Phosphorylase.http://www.creative-
enzymes.com/product/Native-Bacillus-Sp-Purine-
Nucleoside-Phosphorylase_760.html
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