Technology of Sirolimus Derivatives
Other Names: Sirolimus(西罗莫司); RAPA; RPM; AY-22989; NSC-226080; Rapamune
CAS Registry Number: 53123-88-9
Rapamycin is a macrolide immunosuppressant isolated from Streptomyces hygroscopicus.
Other Names: 40-Epi-(N1-tetrazolyl)-rapamycin; ABT-578
CAS Registry Number: 221877-54-9
Molecular Formula: C52H79N5O12
Molecular Weight: 966.2
Zotarolimus is a macrolide immunosuppressant produced by semi-synthesis from rapamycin (sirolimus).
Temsirolimus is a macrolide anticancer agent produced by semisynthesis from Rapamycin.
Biolimus A9 is a macrolide immunosuppressant produced by semi-synthesis from rapamycin (sirolimus).
Everolimus [CAS # 159351-69-6] 依维莫司
Everolimus is a macrolide immunosuppressant produced by semisynthesis from sirolimus.
CAS Registry Number: 137071-32-0
Pimecrolimus is a macrolide immunosuppressant produced by semisynthesis starting from ascomycin.
Ascomycin子囊霉素 (also known as FK520) is a macrolide immunosuppressant produced by fermentation of Streptomyces tsukubaensis or Streptomyces hygroscopicus var. ascomyceticus.
Tacrolimus他克莫司 (also known as FK506) is a secondary metabolite isolated from Streptomyces tsukubaensis. It is a non-polar macrolide with immunosuppressant activity and originally developed by Fujisawa.
Product Name: A40926-B0
CAS Number: 102961-72-8 Molecular Formula: C83H88CL2N8O29 Molecular Weight: 1732.56
A40926-B0 is a glycopeptide antibiotic structurally similar to teicoplanin and ancomycin. It is used as precursor for synthesis of dalbavancin. It inhibits peptidoglycan synthesis in the cell wall of gram-positive bacteria.
White or off-white solid; Soluble in water, slightly soluble in methanol, ethanol; insoluble in non-polar organic solvents. HPLC purity: 80% min.