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喷他霉素(Pentamycin)
 

喷他霉素,又称戊霉素


Pentamycin, also called fungichromin, is a macrolide antibiotic. Pentamycin is a polyene antifungal antibiotic obtained from Streptomyces pentaticus. It is used in the treatment of vaginal candidiasis and for the protozoal infection trichomoniasis. A 3 mg vaginal pessary is inserted once or twice daily for 5-10 days.


(3R,4S,6S,8S,10R,12R,14R,15R,16R,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,15,16,27-nonahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one


喷他霉素。由戊霉素轮丝链霉菌(Streptomyces pentaticus)等产生的一种多烯类抗生素。溶于甲醇、吡咯、丁醇,不溶于水、乙酸丁酯、己烷。具有抗真菌活性。临床用于治疗滴虫病及念珠菌所引起的阴道炎。贮放时间较短。

发表时间:2010-12-21
 
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