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ITEMS



TECH DATA



REMARKS



IMMUNOSUPPRESSIVE AGENT



 



 



他克莫司



Tacrolimus



 



Final Titre:600-700mg/L



Fermentation time:168hrs



Recovery:40%



FK506



霉酚酸



Mycophenoic acid



Final Titre:15g/L



Fermentation time:264hrs



Recovery:70%



Intermediate



for MMF



环孢菌素 A



Cyclosporin A



Final Titre: 10g/L



Fermentation Time:168hrs



Recovery:70%



 



雷帕霉素(西罗莫司)



Rapamycin(Sirolimus)



Final Titre: 600-800g/L



Fermentation Time:216hrs



Recovery:60%



Or intermediate



for Zotarolimus,



Everolimus



and



子囊霉素



Ascomycin



Final Titre: 500g/L



Fermentation Time:216hrs



Recovery:60%



FK520



Or Intermediate



for Pimecrolimus



ANTIBIOTICS



 



 



阿莫西林



AMOXICILLIN



By enzyme process



 



万古霉素



Vancomycin



Final Titre:9-10g/L



Fermentation Time: 150hrs



Recovery:>70%



 



替考拉宁



Teicoplanin



Final Titre:4-5g/L



Fermentation Time: 150hrs



Recovery:>70%



 



达托霉素



Daptomycin



Final Titre2.0g/L



Fermentation Time: 200hrs



Recovery:>40%



Or cubicin



莫匹罗星



Mupirocin



Final Titre:4-5g/L



Fermentation Time:60-70hrs



Recovery:>75%



 



Pneumocandin B0



Final Titre:1.7g/L



Fermentation Time: 11-12days



Recovery:>60%



Caspofungin



雷莫拉宁



Ramoplanin



Final Titre:3g/L



Fermentation Time: 200hrs



Recovery:>60%



 



普那霉素(原始霉素)



Pristinamycin



Final Titre:8/L



Fermentation Time: 150hrs



Recovery:>70%



 



克拉维酸(棒酸)



Clavulanic acid



Final Titre:6g/L



Fermentation Time:105hrs



Recovery:55%



 



头孢菌素 C



Cephalosporin C



Final Titre:40g/L



Fermentation Time:168hrs



Recovery:80%



各种头孢类中间体



青霉素G



Penicillin G



Final Titre:120000g/L



Fermentation Time:220hrs



Recovery:80%



 



红霉素



Erythromycin



Final Titre:9-10g/L



Fermentation Time:156hrs



Recovery:60%



依托红霉素、琥乙红霉素、地红霉素、罗红霉素、阿奇霉素和克拉霉素的中间体



去甲金霉素



Demethylchlortetracycline (DMCT)



Final Titre:16g/L



Fermentation Time:200hrs



Recovery:75%



Intermediate for



Minocycline,



Tigecylcine



林可霉素(洁霉素)



Lincomycin



Final Titre:9-10g/L



Fermentation Time:200hrs



Recovery:80-90%



克林霉素中间体



Clindamycin



杆菌肽



Bacitracin



Final Titre:1200U/ml



Fermentation Time:50-60hrs



Recovery:95%



Zinc Bacitracin for



Animal feed additive



那西肽



Nosiheptide



Final Titre:1700-2000U/ml



Fermentation Time:50hrs



Recovery:95%



Animal feed additive



两性霉素B



Amphotericin B



Final Titre:10000U/ml



Fermentation Time:130-140hrs



Recovery:75%



 



阿维拉霉素(卑霉素)



Avilamycin



Final Titre:7-8g/L



Fermentation Time:268hrs



Recovery:95%



Animal feed additive



恩拉霉素



Enramycin



Final Titre:8-10g/L



Fermentation Time:260hrs



Recovery:95%



Animal feed additive



卡那霉素



Kanamycin



Final Titre:25g/L



Fermentation Time:240hrs



Recovery:85%



 



卷曲霉素



Capreomycin



Final Titre:11000U/ml



Fermentation Time:150-160hrs



Recovery:75%



 



庆大霉素C



Gentamicin C



Final Titre:5-6g/L



Fermentation Time:14days



Recovery:75%



 



庆大霉素B



Gentamycin B



Final Titre:1000Mmg/L



Fermentation Time:120-130hrs



Recovery:75%



异帕米星



(Isepamicin)



多粘菌素B



Polymyxin B



Final titre 2.5 g/l



Fermentation time 72 hrs



Recovery yield 70%



 



粘杆菌素 E



Polymyxin E



Final titre 600000U/ml



Fermentation time 96 hrs



Recovery yield 75%



 



泰乐菌素



Tylosin



Final titre 15000 U/l



Fermentation time 180 hrs



Recovery yield 70%



 



巴龙霉素



Paromomycin



Final titre 8g/l



Fermentation time170 hrs



Recovery yield 70%



 



制霉菌素



Nystatin



Final titre 300,000IU/ml



Fermentation time 280 hrs



Recovery yield 85%



 



盐霉素



Salinomycin



Final titre 80g/l



Fermentation time 268 hrs



Recovery yield 90%



 



金霉素



Chlortetracycline



Final titre 50g/l



Fermentation time 200 hrs



Recovery yield 90%



 



四环素



Tetracycline



Final titre 40g/l



Fermentation time 200 hrs



Recovery yield 90%



 



土霉素



Oxytetracycline



Final titre 40g/l



Fermentation time 200 hrs



Recovery yield 90%



 



链霉素



Streptomycin



Final titre 28,000U/ml



Fermentation time 200 hrs



Recovery yield 80%



 



利福霉素



Rifamycin



 



Final titre 30g/l



Fermentation time 220 hrs



Recovery yield 75%



 



黄霉素



Flavomycin



Final titre 8g/l



Fermentation time 168 hrs



Recovery yield 90%



 



截短侧耳素



Pleuromutilin



Final titre 14000U/ml



Fermentation time 300 hrs



Recovery yield 80%



泰妙菌素



Tiamulin



大观霉素



Spectinomycin



Final titre 7000-10000U/ml



Fermentation time 130-150 hrs



Recovery yield 70%



 



莫能菌素



Monensin



38000u/ml



Final titre 6500-8000U/ml



Fermentation time 140-170 hrs



Recovery yield 70-80%



 



妥布霉素



Tobramycin



Final titre 6500-8000U/ml



Fermentation time 140-170 hrs



Recovery yield 70-80%



 



安普霉素



Apramycin



Final titre 6500-8000U/ml



Fermentation time 140-170 hrs



Recovery yield 70-80%



 



尼可霉素



Nikkomycin



Final titre 7-8 g/l



Fermentation time 70 hrs



Recovery yield 80%



 



麦角酸



Lysergic acid



Final titre 7-8 g/l



Fermentation time 360 hrs



Recovery yield 70%



For cabergoline and nicergoline



夫西地酸



Fusidic Acid



Final titre 4-5 g/l



Fermentation time 200 hrs



Recovery yield 40%



 



麦迪霉素



Medimycin



 



Final titre 18g/l



Fermentation time 200 hrs



Recovery yield 75%



 



莫能菌素



Monensin



Final Titre:40000U/ml



Fermentation Time: 300hrs



Recovery:95%



 



马杜霉素



Maduramicin



Final Titre:612000U/ml



Fermentation Time: 200hrs



Recovery:95%



 



利福霉素



RIFAMYCIN



Final Titre:25g/L



Fermentation Time:240hrs



Recovery:80%                                        



 



磷霉素



Fosfomycin



 



 



氯霉素



Chloramphenicol



 



 



灰黄霉素



Griseofulvin



 



 



螺旋霉素



Spiramycin//Rovamycin



Final Titre:6000U/ml



Fermentation Time: 160hrs



Recovery:75%



 



小诺霉素



Micronomicin



 



 



维吉尼亚霉素



Virginmycin



R&D



 



亮菌甲素(假蜜环菌素)



Armillarisin a.



 



 



美贝霉素



Milbemycin



Seeking



 



莫西菌素



Moxidectin



 



 



道拉菌素



Doramectin



 



 



土拉霉素



Tulathromvcin



Seeking



 



米卡芬净



micafungin



R&D



 



阿尼芬净



anidulafungin



R&D



 



 



 



 



Bio-PESTICIDE



 



 



阿维菌素



Abamectin



 



Final Titre:4.5g/l



Flask:4.8-5.0g/L



Time:240hrs



Recovery:80%



Including



its derivatives



多杀菌素



Spinosad



Final Titre:12g/L



Fermentation Time:200-240hrs



Recovery:80%



Bio-pesticide



井冈霉素



Validamycin



Final Titre: 3-4g/L



Fermentation Time:60-70hrs



Recovery:80%



 



春雷霉素



Kasugamycin



Final Titre: 8000-1000U/ml



Fermentation Time:192hrs



Recovery80%



 



多抗霉素



Polyoxin



Final Titre: 5000U/ml



Fermentation Time:192hrs



Recovery:80%



 



脱落酸



Abscisic Acid (ABA)



Final Titre:1.6g/L



Fermentation Time:70-72hrs



Recovery:60-65%



Plant hormone



Biopesticide



赤霉素



Gibberellin (GA3)



Final Titre:2.5-2.8g/L



Fermentation Time:150-160hrs



Recovery:80%



 



中生霉素



zhongshengmycin



Final Titre:10g/L



Fermentation Time:1200hrs



Recovery:80%



 



枯草芽孢杆菌



Bacillus subtilis



Final Titre6000U/ml



Fermentation Time:150-160hrs



Recovery:80%



 



苏云金杆菌



Bacillus thuringiensis



Final Titre:5500g/ml



Fermentation Time:150-160hrs



Recovery:80%



 



浏阳霉素



Liuyangmycin



 



 



宁南霉素



Ningnanmycin



 



 



链霉素



streptomycin



 



For agriculture



ANTI-DIABETES



 



 



米格列醇



Miglitol



Final Titre:2g/L



Fermentation Time:70-72hrs



Recovery:60-65%



Synthesis:90%



 



阿卡波糖



Acarbose



Final Titre:5-6g/L



Fermentation T, ime:130-150hrs



Recovery:30-40%



 



伏格列波糖



Veglibose



Chemical synthesis



 



 



 



 



ANTI-TUMOR



 



 



柔红霉素



Daunomycin



Final Titre:1.5g/L



Fermentation Time:168hrs



Recovery:>67%



For epirubicin,



   Idarubicin,



   doxorubicin



洋红霉素



Carminomycin



Final titre 0.15 g/l



Fermentation time 168 hrs



Recovery yield 65%



 



偏端霉素



Distamycin



Final titre 2g/l



Fermentation time 120 hrs



Recovery yield 52%



 



博莱霉素



Bleomycin



Final titre 4g/l



Fermentation time 168 hrs



Recovery yield 70%



 



紫杉醇



Paclitaxel



Final titre 200mg/l



Fermentation time 120 hrs



Recovery yield 50%



 



丝裂霉素C



Mitomycin C



Final titre 1000mg/l



Fermentation time 200 hrs



Recovery yield 50%



 



阿霉素



Doxorubicin



Chemical synthesis



Or fermentation



棕霉素



Bruneomycin



Final titre 150mg/l



Fermentation time 144 hrs



Recovery yield 60%



 



放线菌素D



Dactinomycin D



Chemical synthesis



 



表阿霉素



Epirubicin



Chemical synthesis



 



伊达比星



Idarubicin



Chemical synthesis



 



吡柔比星



Pirarubicin



Chemical synthesis



 



 



 



 



ANTI-CARDIVASCULAR



 



 



洛伐他汀



Lovastatin



Final Titre:16g/L



Fermentation Time:168hrs



Recovery:70%



 



美伐他汀



Compactin



Final Titre:10g/L



Fermentation Time:200-220hrs



 



普伐他汀



Pravastatin



Final Titre: 8.0g/l



Conversion rate:70%



Cycle time: 120-144



 



阿托伐他汀



Atorvastatin



Chemical synthesis



 



瑞舒伐他汀



Rosuvastatin



Chemical synthesis



 



辛伐他汀



Simvastatin



Chemical synthesis



 



氟伐他汀



Fluvastatin



Chemical synthesis



 



 



 



 



ORGANNIC ACID



 



Biobased chemicals



衣康酸



Itaconic Acid



Acid:>6%



Cycle time:40-50hrs



Conversion:>50%



Fermentation data:1.4g/L/hr



The product gets to Pfizer



柠檬酸



Citric acid



 



 



莽草酸



Shikimic Acid



Titre: 25g/L



 



L-乳酸



L-Lactic acid



Acid:16-18%



Conversion rate; 90%



 



丙酮酸



Pyruvic acid



Titre:55-65g/L



Conversion rate:55-60%



Fermentation time:60hr



Recovery:70%



 



长链二元酸



Long-chain dicarbxylic acid



DCA13-18: 180g/L,



Fermentation time:5-6days



 



 



 



 



Bio-based products



 



 



1,3-丙二醇



1,3-propandiol(PDO)



Titre: 85g/L



Conversion rate:60%



Productivity:1.2-1.4g/LH



Chemical



2,3-丁二醇



2,3-butandiol



50-65g/L



By product from PDO



丁醇



Butanol



20g/L



 



甘油



Glycerol



Titre:160g/l



Time:78hrs



Productivity:2g/LH



Mass conversion rate: 48.6%



Chemical



丙烯酰胺



Acrylamide



Enzyme activity: 1 0g/ml



Acrylonitrile consumption: 0.75t/t



Conversion rate: 99.9%



Chemical



 



烟酰胺



Nicotinamide



Enzyme activity: 8g/ml



Nicotinonitrile consumption: 0.85t/t



Conversion rate: 99.999%



Assay: 100%



Chemical



羟基乙酸



Hydroxyacetic acid



Enzyme activity: 0.1g/ml



Glycolonitrile consumption: 0.78t/t



Conversion rate: 99.9%



Assay: 99.5% ( pharma grade)



Chemical



黄原胶



Xanthan



Final Titre:5-6g/L



Fermentation Time:36hrs



Recovery:80%



 



琥珀酸(丁二酸)



Succinic acid



 



 



苹果酸



Malic acid



 



 



牛磺酸



Taurine



 



 



乙酸(醋酸)



Acetic acid



 



 



聚羟基脂肪酸



Polyhydroxyalkanoates (PHAs)



 



degradable plastics



聚乳酸



Polylactic acid, PLA



 



 



 



 



 



VITAMIN AND CAROTENOID



 



 



维生素B2



Vitamin B2



Final titre 30g/l



Fermentation time 72 hrs



Recovery yield 80%



 



维生素B12



Vitamin B12



Final titre 250mg/l



TIME:180hrs



 



维生素C



Vitamin C



Final titre 11-12g/l



Fermentation time 60 hrs



Conversion rate; 90%



 



番茄红素



Lycopene



Final Titre:>1.0g/L



 



胡萝卜素



Beta Carotene



Final Titre:2.5-3.0g/L



Fermentation Time:72hrs



Recovery:75-80%



 



虾青素



Astaxanthin



Final Titre:2g/L



 



维生素D2



Vitamin D2



Light reaction



 



维生素D3



Vitamin D3



Light reaction



 



维生素A



Vitamin A



chemical synthesis



 



维生素H



Vitamin H



By fermentation



Or chemical synthesis



Biotin



HORMONE



 



Biotransformation



Hormone



 



 



雄烯二酮



Anostenedione(AD)



Final titre 15 g/l



Fermentation time 200 hrs



Recovery yield 75%



Intermediate



 



雄二烯二酮



androsta-1,4-diene-3,17-dione



(ADD)



Final titre 10 g/l



Fermentation time 200 hrs



Recovery yield 72%



Intermediate



 



泼尼松龙



Prednisolone



 



Finaltitre>20g/L(Maximum 70g/L)



time:5-8 hrs



conversion: 97~100%



 



睾丸素



Testosterone



Final Titre 5g/L



 



去氢甲睾酮



Methandrostenolone



Final Titre 10g/L



 



Pregna 1,4,9,17 acetate



Final Titre 5g/L



 



Pregna 1,2,9,21



Final Titre 5g/L



 



螺内酯



SPIRONOLACTONE



 



 



依普利酮



Eplerenone



 



 



ANTISPETIC



 



 



异抗血酸



D-isoascorbate



Productivity:18-20g/L



 



那他霉素



Natamycin 



Final Titre:8-10g/L



Fermentation Time:140-150hrs



antiseptic



乳酸链球菌素



Nisin



 



Natural antiseptic



 



 



 



HEALTHCARE



 



 



谷胱甘肽



Glutathione(GSH)



Titre: 5g/L



Biomass:140g/L



Fermentation time 72 hrs



Recovery yield 45%



 



辅酶Q10



Coenzyme Q10



Final titre2.5-3.0 g/l



Fermentation time 96 hrs



Recovery yield 60%



 



透明质酸



Hyaluronic acid (HA)



Final Titre:6-7g/L



Fermentation Time:20hrs



Recovery:90%



Best performance is 10g/L



花生四烯酸



Arachidonic acid (AA)



 



Final titre 9+1.5 g/l



Fermentation time 192hrs



Recovery yield: 65%



Food additives



Healthcare



S-腺苷甲硫氨酸



S-adenosylmethionine (SAMe)



 



 



二十二碳六烯酸



Docosahexaenic Acid(DHA)



 



 



 



 



 



Others



 



 



普鲁兰



Pullulan



Titre:60-70g/L



Conversion:60-70%



 



灵芝多糖



Polysaccharide



Final Titre: 1.5g/l



Cordyceps.sinensis



赤藓糖醇



Erythritol



 



excipient



Instant Active Yeast



 



Food processing



Yeast extract



 



Food savor



麦角固醇



Ergosterol



 



For Vitamin D



Alpha-cyclodextrin



 



excipient



Beta- cyclodextrin



 



excipient



肌苷



Inosine



Productivity :100g/L
time: 90小时
conversion 35%
recovery: 90%



 



鸟苷



Guanosine



Titre :50-60g/L.
time:72小时
conversion: 25%
recovery: 90%



 



WEIGHT LOSING



 



 



尼波司他汀



Lipstatin



Final Titre:8-10g/L



Fermentation Time:168hrs



Recovery:75%



Conversion:77.8%



Orlistat(奥利司他)



Weight losing



 



 



 



Enzymes



 



酶制剂



Phytase



20000U/ml



 



Xylase



Inquiry



 



Celluase



Inquiry



 



Amylase



Inquiry



 



Protease



Inquiry



 



Acylase,



Inquiry



 



Many other,Etc



Inquiry



 



Penicillin G amidase



 



 



 



 



 



Amino acids



Folder & food additives



 



Medicine, Healthcare



色氨酸



L-Tryptophan



Final titer 25-30 g/l



 



苯丙氨酸



L-Phenylalanine



Final titer 40 +/- 2 g/l



 



苏氨酸



L-Threonine



Final titer 120 g/l



 



精氨酸



L-Arginine



Final titre > 60 g/l



 



缬氨酸



L-Valine



Final titre 52 +/- 2 g/l



 



赖氨酸



L-Lysine



Final titre 160 +/- 10 g/l



 



亮氨酸



L-Leucine,



Final Titre:40g/L



Fermentation Time: 65hrs



Recovery:70%



Conversion:20%



 



异亮氨酸



L-isoleucine



Final Titre:30g/L



Fermentation Time: 25hrs



Recovery:80%



 



谷氨酰胺



L-Glutamine



Final Titre:80g/L



Fermentation Time: 65hrs



Recovery:75%



 



谷氨酸



Glutmate



productivity:180-200g/L.
time:36hrs
conversion rate:70%
recovery :95%



 
发表时间:2009-5-26
 
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